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Item type:Publication, Bioactive membranes of polymeric micro and nanocomposites prepared with the natural anionic marine polysaccharide (Alginate) functionalized with extracts of cat’s claw (Uncaria tomentosa) and Aloe vera(Trans Tech Publications Ltdttp@transtec.ch, 2020-01-01)In this research, the nanostructured alginate (AL) membranes were prepared with natural bioactive compound, Cat's claw (Uncaria tomentosa) extract (UT). UT is broadly used as an anti-inflammatory agent and the effect on the treatment of Rheumatism was proved by many scientists. For this reason, we added this bioactive compound in the process of AL membrane formulation to improve the biological activities. 2-dimentional (2-D) and 3-dimentional (3-D) AL membranes were prepared with and without addition of UT extracts. 3-D AL membranes were prepared using ultrasound with high intensity. The wettability of AL membranes depending on the concentration of AL was studied by measuring contact angle and surface energy. Stabilization agent, poloxamer 407, was used to improve the stability of AL nanoemulsion. The effects of UT in 3-D AL membranes were studied by measuring swelling behavior and contact angle. The surface morphology was measured with scanning electron microscopy (SEM). Comparing to 2-D AL membranes, 3-D AL membranes presented rougher surface due to AL nanoparticles presence. When UT was incorporated in AL membranes, strong antioxidant activity and higher contact angle and swelling ratio were observed than non-UT incorporated AL membranes. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Ultrasound-assisted anthocyanins extraction from purple cabbage for optical biosensor of wound healing monitoring(Trans Tech Publications, 2024-03-29)The ethanol-water based extraction of phenolic bioactive components, anthocyanins, from purple cabbage (PC) was carried out. Ultrasound assisted extraction was performed and each cycle was set to 3 minutes. UV-visible absorbance was evaluated at each cycle (total 3 cycles) and the intensity of absorbance at 546~550 nm was interpreted as the extraction efficiency of anthocyanin. The pH sensibility of PC extracts was evaluated at pH 4, 5, 6, 7, and 8 and measured with UV-Visible spectrometry. Each pH condition, the extracts presented different color shades and wavenumbers of maximum absorbance proving their pH sensibility. Antioxidant activity of PC extract was evaluated and the excellent inhibition capacity was observed (~98%). PC extract was then embedded in alginate membrane to use as wound dressing materials. Alginate membrane with PC extract also presented high pH sensibility showing remarkable color changes after exposure to different pH environments.