3. Producción

Browse

Settings

Access type: UnknownSubject: search.filters.subject.Antibacterial activity

Search Results

Now showing 1 - 3 of 3
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Effect of the concentration and the type of dispersant on the synthesis of copper oxide nanoparticles and their potential antimicrobial applications
    (American Chemical Society, 2021-07-27)
    High Resolution Image Download MS PowerPoint Slide The bactericidal properties of copper oxide nanoparticles have growing interest due to potential application in the medical area. The present research investigates the influence of sodium dodecyl sulfate (SDS) and poly(vinylpyrrolidone) (PVP) on the production of copper oxide nanoparticles prepared from copper sulfate (CuSO 4 ) and sodium borohydride (NaBH 4 ) solutions. Different analytical techniques were used to determine the crystal nature, mean size diameter, and surface morphology of the copper oxide nanoparticles. The X-ray diffraction (XRD) patterns showed formation of nanoparticles of cuprite (Cu 2 O) and tenorite (CuO) when PVP and SDS were added at the beginning of the reaction. In fact, when the Cu/PVP ratio was 1.62, Cu 2 O nanoparticles were obtained. In addition, nanoparticles of CuO were synthesized when the Cu/PVP ratios were 0.54 and 0.81. On the other hand, a mixture of copper oxides (CuO and Cu 2 O) and cuprite (Cu 2 O) was obtained when PVP (Cu/PVP = 0.81 and 1.62) and SDS (Cu/SDS = 0.90) were added 30 min after the beginning of the reaction. Transmission electron microscopy (TEM) images show agglomerated nanoparticles with a size distribution ranging from 2 to 60 nm, while individual particles have sizes between 4.1 ± 1.9 and 41.6 ± 12.8 nm. The Kirby–Bauer method for the determination of antibacterial activity shows that small CuO (4.1 ± 1.9 nm) and Cu 2 O (8.5 ± 5.3 nm) nanoparticles inhibit the growth of Escherichia coli, Staphylococcus aureus MRSA, S. aureus and Pseudomonas aeruginosa bacteria. The antibacterial test of cotton fabric impregnated with nanoparticles shows positive results. The determination of the optimal ratio of copper oxide nanoparticles per cm 2 of fabric that are able to exhibit a good antibacterial activity is ongoing.
      1
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Copper Tannate (CuTn) based coating on 3D printed face masks
    (Trans Tech Publications Ltd, 2022-01-01)
    The impact of COVID-19 crisis on global supply chains caused a critical shortage of essential goods like medical devices. Additionally, massive consumption increased mask contamination and waste. 3D printing has become a fast and versatile manufacturing alternative that prevents a single use of masks. However, SARS-CoV-2 virus can persist on plastic surfaces for days. This study proposes the optimization of 3D printed masks, by applying a coating rich in hydrolyzable tannins and copper, in order to diminish the virus presence. Different paints were formulated with copper tannate and applied on thermoplastic polyurethane 3D panels to test bacterial stability. Results showed a significant reduction of colony-forming units on coated polymeric surfaces. Paints pigmented with copper tannates could improve the protection provided by printed masks, even against the COVID-19 virus.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Development and Characterization of a Curcumin-Loaded Alginate-Xanthan Gum Hydrogel for Antibacterial Activity and Controlled Drug Release
    (Trans Tech Publications Ltd, 2025)
    This article describes the development and characterization of a curcumin-loaded alginate-xanthan gum hydrogel, designed to provide both antibacterial activity and controlled drug release.The hydrogel formulation consisted of 4% (w/v) alginate, 4% (w/v) xanthan gum, and 500 μg/mL of curcumin. Sterilization was achieved through ethanol immersion, UV irradiation, and autoclaving, with the latter two methods proving to be the most effective in maintaining long-term sterility. Antibacterial efficacy was tested against Staphylococcus aureus, demonstrating a significant inhibition zone around the hydrogel. The curcumin release profile indicated a sustained release over 72 hours, suggesting its suitability for prolonged antibacterial applications.
      4